Acetylcistein 600 mg 10 Sachets

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6221042216011
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Quick Overview
N-Acetylcysteine has a mucolytic activity which acts directly by splitting the disulfide bonds of mucoproteins and thus reduces the sputum viscosity and facilitates its expectoration by the tracheo-bronchial cilia.
Composition: Acetylcysteine ................................. 600 mg Inactive ingredients for the 600 mg: Citric acid anhydrous, mannitol, sodium bicarbonate, sodium carbonate anhydrous, trimagnesium dicitrate anhydrous, saccharin sodium, aspartame, povidone k25, allura red & blackberry flavor. Properties: N-Acetylcysteine has a mucolytic activity which acts directly by splitting the disulfide bonds of mucoproteins and thus reduces the sputum viscosity and facilitates its expectoration by the tracheo-bronchial cilia. N-Acetylcysteine improves the pulmonary defense mechanism, phagocytic capacity of alveolar macrophages and so protects lungs from inflammation via its direct-antioxidant property and indirectly as a precursor of glutathione synthesis. Phamacokinetics: Following the oral administration, acetylcistein is readily absorbed from the gastrointestinal tract with peak plasma concentration attained within 2-3 hours. Concentrations in the lungs are similar to those in plasma. About 20% of a dose is excreted in the urine daily. "Acetylcistein effervescent instant" is a new pharmaceutical form that ensures rapid dissolution, maximal absorption, high bioavailability in a perfectly calibrated dosage. Indications: Mucolytic therapy in cases associated with hyper-viscous mucous secretions. Upper respiratory tract disorders such as Chronic sinusitis and secretary otitis media (glue ear) Broncho-pulmonary Diseases e.g. Bronchitis, Pneumonia, Asthmatic Bronchitis, Bronchiectasis, cystic fibrosis (mucoviscidosis), Pneumoconiosis and Emphysema. The routine cleansing of tracheostomy during anesthesia. Manifestations associated with smoking & exposure to other irritant inhalers. Contraindications: Hypersensitivity to the active ingredient or to any of the constituents. Acetylcistein is contraindicated for children under 2 years old. Side Effects: It is well tolerated. rarely in overdoses Nausea, vomiting, heart burn , diarrhea, bronchospams, angioedema, skin eruption, tachycardia, tinnitus and precipitation of cystine, oxalate or urate renal stones especially with acidic urine. Warnings: After proper administration of acetylcysteine, an increased volume of liquefied of bronchial secretions may occur. When cough is inadequate, the open airway must be maintained by mechanical secretion if necesary. When there is a mechanical block due to foreign body or local accumulation, the airway should be cleaned by end tracheal aspiration with or without bronchoscopy. Asthmatic treated with Acetycysteine should be watched carefully. Most patients with bronchospasm are quickly relieved by the use of bronchodilator given by nebulization. If bronchospasm progresses, the medication should be discontinued immediately. Drug interactions: Avoid concomitant administration (two hours interval) of the drug with the following: - tetracycline hydrochloride, antitussives & nitroglycerin. Precautions: Acetylcysteine must be used with cautions in patients with history of peptic ulceration and avoided in patients with active ulcer, asthma or hyperoxaluria. Maintain fluids intake (6-8 glasses of water daily) to avoid formation formation of cystine renal stones. Avoid diuretics or forces diuresis. - Caution should be taken in patients who complain from hypertension, heart failure, renal disease, oedema and all cases that need salt restriction. Use during pregnancy and lactation: Acetylcistein should only used if clearly needed due to lack of well - controlled studies. Over dosage: No particular symptoms of over dosages has been observed, treatment should be symptomatic and supportive. Storage: Keep at temp. not exceeding 30°C. Keep medicine out of reach of children. Presentation: 10 tetra-laminated aluminum foil sachets packed in a carton box with a pamphlet.
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Acetylcistein 600 mg 10 Sachets