Active ingredient dutasteride Therapeutic indications Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH). Reduction in the risk of acute urinary retention (AUR) and surgery in patients with moderate to severe symptoms of BPH. Posology and method of administration Avodart can be administered alone or in combination with the alpha-blocker tamsulosin (0.4mg) Adults (including elderly): The recommended dose of Avodart is one capsule (0.5 mg) taken orally once a day. The capsules should be swallowed whole and not chewed or opened as contact with the capsule contents may result in irritation of the oropharyngeal mucosa. The capsules may be taken with or without food. Although an improvement may be observed at an early stage, it can take up to 6 months before a response to the treatment can be achieved. No dose adjustment is necessary in the elderly. Renal impairment The effect of renal impairment on dutasteride pharmacokinetics has not been studied. No adjustment in dosage is anticipated for patients with renal impairment Hepatic impairment The effect of hepatic impairment on dutasteride pharmacokinetics has not been studied so caution should be used in patients with mild to moderate hepatic impairment (see section 4.4 and section 5.2). In patients with severe hepatic impairment, the use of dutasteride is contraindicated 4.3 Contraindications Avodart is contraindicated in: - women and children and adolescents - patients with hypersensitivity to dutasteride, other 5-alpha reductase inhibitors, soya, peanut or any of the other - patients with severe hepatic impairment.
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تداوي اكسبرس - خدمة التوصيل السريع من تداوي. احصل علي طلبك في نفس اليوم او اليوم التالي حسب العنوان في القاهرة. او في فتره من يوم الي سبعة ايام للمحافظات الاخري في مصر
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